Single-dose rifampicin and BCG to prevent leprosy
نویسندگان
چکیده
منابع مشابه
Single-dose rifampicin, oflaxicin and minocycline (ROM) therapy for single leprosy lesions.
presumably in a pessimistic mood about understanding leprosy, while he has distinctly expressed his optimism about the disappearance of the disease. Indeed since he said this in 1 994, the situation has improved (and not deteriorated) with special strategies spearheaded by WHO to unearth new cases and implement short course chemotherapy. If we had any qualms we might never have got started. As ...
متن کاملThe combined effect of chemoprophylaxis with single dose rifampicin and immunoprophylaxis with BCG to prevent leprosy in contacts of newly diagnosed leprosy cases: a cluster randomized controlled trial (MALTALEP study)
BACKGROUND Despite almost 30 years of effective chemotherapy with MDT, the global new case detection rate of leprosy has remained quite constant over the past years. New tools and methodologies are necessary to interrupt the transmission of M. leprae. Single-dose rifampicin (SDR) has been shown to prevent 57% of incident cases of leprosy in the first two years, when given to contacts of newly d...
متن کاملCost-Effectiveness of a Chemoprophylactic Intervention with Single Dose Rifampicin in Contacts of New Leprosy Patients
BACKGROUND With 249,007 new leprosy patients detected globally in 2008, it remains necessary to develop new and effective interventions to interrupt the transmission of M. leprae. We assessed the economic benefits of single dose rifampicin (SDR) for contacts as chemoprophylactic intervention in the control of leprosy. METHODS We conducted a single centre, double blind, cluster randomised, pla...
متن کاملIngestion of a Single Dose of Rifampicin
Liver function and serum concentrations of rifampicin, a highly cholephilic antibiotic, have been studied after ingestion of a single dose of 600 mg of rifampicin in 12 patients, six of them having a normal liver and six a cirrhotic, and during treatment with 600 mg of rifampicin per day for 17 days in eight patients, four of them having a normal liver and four a cirrhotic. Rifampicin produced ...
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Introduction: Esophageal cancer is among the most common malignancies. Hospital mortality in the past decade reduced; but its morbidity is still high. Pulmonary complications are the most common complications after esophageal resection. In this study we examined the effect of steroids administration during surgery to reduce postoperative morbidity with a focus on respiratory complications.Mater...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2020
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2020.01.054